The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-k
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
A novel inhibitor of NF-κB-inducing kinase prevents bone loss by inhibiting osteoclastic bone resorption in ovariectomized mice - ScienceDirect
Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation - ScienceDirect
Small molecule approaches to treat autoimmune and inflammatory diseases (Part I): Kinase inhibitors - ScienceDirect
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NIKing BAFF's limelight | Nature Reviews Rheumatology
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Noncanonical NF-κB Signaling in Health and Disease: Trends in Molecular Medicine
Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses | Scientific Reports
Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies
The structure of Amgen NIK compounds. | Download Scientific Diagram
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Medicinal Chemistry Strategies for the Development of Kinase Inhibitors Targeting Point Mutations | Journal of Medicinal Chemistry
Transcreener ADP Assay Enables Evaluation of NIK Inhibitors in Lupus Drug Discovery - BellBrook Labs
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic
